This work supports the need to develop selective HDAC1/2 inhibitors for clinical application and, more broadly, illuminates the power of integrating expression-based screening with DOS chemistry to provide new biological insights - Expression of TNF inhibitor in Senescence and Aging

This work supports the need to develop selective HDAC1/2 inhibitors for clinical application and, more broadly, illuminates the power of integrating expression-based screening with DOS … Continue reading This work supports the need to develop selective HDAC1/2 inhibitors for clinical application and, more broadly, illuminates the power of integrating expression-based screening with DOS chemistry to provide new biological insights